Concepedia

Chondrogenesis Mediated by PP <sub>i</sub> Depletion Promotes Spontaneous Aortic Calcification in NPP1−/− Mice

Kristen Johnson, Monika D. Polewski, Deborah Van Etten, Robert Terkeltaub

Arteriosclerosis Thrombosis and Vascular Biology · 2004 · 175 citations · 31 references

DOI

Abstract

NPP1 and PP(i) deficiencies modulate phenotype plasticity in artery SMCs and chondrogenesis in mesenchymal precursors, thereby stimulating artery calcification by modulating cell differentiation.

References

31

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Nathan Bucay, Ildiko Sarosi, Colin R. Dunstan et al. · Genes & Development · 1998 · 2.5K citations · Full text

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Phosphate Regulation of Vascular Smooth Muscle Cell Calcification

Shuichi Jono, Marc D. McKee, Charles E. Murry et al. · Circulation Research · 2000 · 1.4K citations

Smooth Muscle Cell Phenotypic Transition Associated With Calcification

Susie A. Steitz, Mei Y. Speer, Gabrielle Curinga et al. · Circulation Research · 2001 · 809 citations

, , +18

Interactions between Sox9 and β-catenin control chondrocyte differentiation

Haruhiko Akiyama, Jon P. Lyons, Yuko Mori–Akiyama et al. · Genes & Development · 2004 · 754 citations · Full text

Role of the Mouse <i>ank</i> Gene in Control of Tissue Calcification and Arthritis

Andrew M. Ho, Michelle D. Johnson, David M. Kingsley · Science · 2000 · 641 citations

, , +15