Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

W. Scott Simonet, Dave Lacey, Colin R. Dunstan, +26

Cell

SclerostinBiochemistryBone Morphogenic ProteinCell SignalingMedicine +11

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Nathan Bucay, Ildiko Sarosi, Colin R. Dunstan, +9

Genes & Development

MechanobiologyMetabolic SyndromeSclerostinDevelopmental BiologyAtherosclerosis +13

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

Toshinori Iwahara, Jiro Fujimoto, Duanzhi Wen, +6

Oncogene

Molecular CharacterizationSignal TransductionMolecular PhysiologyMolecular NeuroscienceMedicine +11

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

Deepa Subramanyam, Samy Lamouille, Robert L. Judson, +4

Nature Biotechnology

Induced Pluripotent Stem CellDevelopmental BiologyPluripotent Stem CellsMir-372 Promote ReprogrammingMultiple Targets +6

Activin A Maintains Pluripotency of Human Embryonic Stem Cells in the Absence of Feeder Layers

Gillian M. Beattie, Ana D. Lopez, Nathan Bucay, +4

Stem Cells

Feeder LayersEmbryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyCell Specialization +10

Maintenance of Pluripotency in Human Embryonic Stem Cells Is STAT3 Independent

Rohan K. Humphrey, Gillian M. Beattie, Ana D. Lopez, +5

Stem Cells

microRNA-1246 Is an Exosomal Biomarker for Aggressive Prostate Cancer

Divya Bhagirath, Thao Ly Yang, Nathan Bucay, +6

Cancer Research

Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.

R Kramer, Nathan Bucay, Darci J. Kane, +3

Proceedings of the National Academy of Sciences

Mouse MyocardialErbb ReceptorsCytoskeletonIg-like DomainCellular Physiology +15

A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice.

W. Scott Simonet, Nathan Bucay, SJ Lauer, +1

Journal of Biological Chemistry

Transgene ExpressionGeneticsHuman Apolipoprotein EMolecular GeneticsTransgenic Mice +19

Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung.

W. Scott Simonet, Nathan Bucay, Hung Q. Nguyen, +6

Proceedings of the National Academy of Sciences

Lung InflammationPathologyPulmonary Alveolar ProteinosisCell ProliferationNormal Pulmonary Morphogenesis +16