Chemical Communications · 2015 · 29 citations · 15 references
Natural SciencesBiophysicsCell BiologyCell BiophysicsMembrane BiophysicsMembrane ScienceBiological MembranesFluorescence MicroscopyMembrane DomainsMembrane MicrodomainsMembrane OrganizationMembrane Phase BehaviorHydrostatic PressureLipid Microdomain PartitioningLiquid - Liquid Phase SeparationLiquid-liquid Phase SeparationMembrane Domain FormationMembrane Domain ImagingMembrane Microdomain OrganizationMembrane Phase Separation
We have imaged the formation of membrane microdomains immediately after their induction using a novel technology platform coupling high hydrostatic pressure to fluorescence microscopy. After formation, the ordered domains are small and highly dynamic. This will enhance links between model lipid assemblies and dynamic processes in cellular membranes.
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Miglena I. Angelova, Dimiter S. Dimitrov · Faraday Discussions of the Chemical Society · 1986 · 1.4K citations