Concepedia
Diabetes · 2008 · 180 citations · 44 references
Open access
Targeting both peripheral and neuronal deficits, Ex-4 is an attractive agent for therapeutic intervention in Huntington's disease patients suffering from diabetes.
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Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
M. Flint Beal, Neil W. Kowall, David W. Ellison et al. · Nature · 1986 · 1.3K citations
Biochemistry, Natural Sciences, Quinolinic Acid +7
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
Susan E. Andrew, Y. Paul Goldberg, Berry Kremer et al. · Nature Genetics · 1993 · 1.1K citations
Genetic Disorder, Genetics, Molecular Biology +8
Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration
Libin Cui, Hyunkyung Jeong, Fran Borovečki et al. · Cell · 2006 · 983 citations · Full text
Transcriptional Regulation, Neurodegenerative Diseases, Mitochondrial Function +10
Hypothalamic insulin signaling is required for inhibition of glucose production
Silvana Obici, Bei B. Zhang, George B. Karkanias et al. · Nature Medicine · 2002 · 856 citations
Obesity, Metabolic Syndrome, Energy Homeostasis +13
Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
Matthew J. During, Lei Cao, David S. Zuzga et al. · Nature Medicine · 2003 · 831 citations
Glucagon-like Peptide-1 Receptor, G Protein-coupled Receptor, Neuropeptide Receptor +3