Proteasome Inhibitors Evoke Latent Tumor Suppression Programs in Pro-B MLL Leukemias through MLL-AF4

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Jordi Barretina, Giordano Caponigro, Nicolas Stransky et al. · Nature · 2012 · 8.5K citations

Medicine, Oncology, Pharmacology +15

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

Christin Tse, Alexander R. Shoemaker, Jessica Adickes et al. · Cancer Research · 2008 · 2K citations · Full text

Medicine, Oncology, Pharmacology +16

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

Ji Luo, Nicole L. Solimini, Stephen J. Elledge · Cell · 2009 · 1.8K citations · Full text

Medicine, Cancer Biology, Oncology +14

BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

Emily H. Cheng, Michael C. Wei, Solly Weiler et al. · Molecular Cell · 2001 · 1.7K citations · Full text

Life Sciences, Cell Biology, Apoptosis +10