Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: Substrate crystal structures at 2Å resolution

An efficient general-purpose least-squares refinement program for macromolecular structures

Dale E. Tronrud, Lynn F. Ten Eyck, B.W. Matthews · Acta Crystallographica Section A Foundations of Crystallography · 1987 · 854 citations · Full text

Natural Sciences, Biophysics, Chemistry +17

Conformation of amino acid side-chains in proteins

Joël Janin, Michael Levitt, Bernard Maigret · Journal of Molecular Biology · 1978 · 790 citations

Life Sciences, Biochemistry, Biophysics +12

Structural basis of the activation and action of trypsin

Robert Huber, Wolfram Bode · Accounts of Chemical Research · 1978 · 673 citations

Natural Sciences, Chemistry, Analytical Chemistry +6

Refined structure of glutathione reductase at 1.54 Å resolution

P. Andrew Karplus, Georg E. Schulz · Journal of Molecular Biology · 1987 · 505 citations

Life Sciences, Biochemistry, Molecular Biology +7

The Structure of Ribonuclease-S at 3.5 A Resolution

Harold W. Wyckoff, Karl D. Hardman, Norma M. Allewell et al. · Journal of Biological Chemistry · 1967 · 351 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17