Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue - Concepedia

Concepedia

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Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue

43

Citations

38

References

2013

Year

Hiroki Takanari, Lukáš Nalos, Anna Stary‐Weinzinger, Kakali De, Rosanne Varkevisser, Tobias Linder, Marien J. C. Houtman, Maaike Peschar, Teun P. de Boer, Richard R. Tidwell,

Cardiovascular Research

Abstract

PA-6 has higher efficiency and specificity to KIR2.x-mediated current than P, lengthens action potential duration, and does not affect channel trafficking at concentrations relevant for complete IK₁ block.

References

	Year	Citations

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