Increased Short-Term Variability of Repolarization Predicts <i>d</i> -Sotalol–Induced Torsades de Pointes in Dogs

Abstract

Proarrhythmia is not related to differences in prolongation of repolarization but corresponds to BVR, here quantified as STV of the left ventricle. STV could be a new parameter to predict drug-induced TdP in patients.