Concepedia

Publication | Open Access

Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer

DOIFull Paper Access

200

Citations

23

References

2013

Year

Takeshi Shimamura, Zhao Chen, Margaret Soucheray, Julián Carretero, Eiki Kikuchi, Jeremy H. Tchaicha, Yandi Gao, Katherine A. Cheng, Travis J. Cohoon, Jun Qi,
Clinical Cancer Research

Abstract

Bromodomain inhibition comprises a promising therapeutic strategy for KRAS-mutant NSCLC with wild-type LKB1, via inhibition of MYC function. Clinical studies of BET bromodomain inhibitors in aggressive NSCLC will be actively pursued. Clin Cancer Res; 19(22); 6183-92. ©2013 AACR.

References

YearCitations

Page 1