The carboxypeptidase-like substrate-binding site in Nna1 is essential for the rescue of the Purkinje cell degeneration (pcd) phenotype

T-coffee: a novel method for fast and accurate multiple sequence alignment 1 1Edited by J. Thornton

Cédric Notredame, Desmond G. Higgins, Jaap Heringa · Journal of Molecular Biology · 2000 · 7K citations

Long-read Sequencing, Novel Method, Functional Genomics +14

An Evolutionary Trace Method Defines Binding Surfaces Common to Protein Families

Olivier Lichtarge, Henry R. Bourne, Fred E. Cohen · Journal of Molecular Biology · 1996 · 1.2K citations

Protein Families, Protein Assembly, Protein Folding +13

Purkinje cell degeneration, a new neurological mutation in the mouse.

Richard J. Mullen, Eva M. Eicher, R. L. Sidman · Proceedings of the National Academy of Sciences · 1976 · 612 citations · Full text

Moderate Ataxia, Purkinje Cell Degeneration, Neurodegenerative Diseases +14

An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies

Lawrence A. Kelley, Stephen P. Gardner, Michael J. Sutcliffe · Protein Engineering Design and Selection · 1996 · 499 citations

Nmr-derived Protein, Biomolecular Structure Prediction, Protein Folding +15

Refined crystal structure of carboxypeptidase a at 1·54 Å resolution

Douglas C. Rees, Mark P. Lewis, William N. Lipscomb · Journal of Molecular Biology · 1983 · 399 citations

Crystal Structure, Biochemistry, Natural Sciences +7