Concepedia

Contribution of High-Mobility Group Box-1 to the Development of Ventilator-induced Lung Injury

Eileen N. Ogawa, Akitoshi Ishizaka, Sadatomo Tasaka, Hidefumi Koh, Hiroshi Ueno, Fumimasa Amaya, Masahito Ebina, Shingo Yamada, Yosuke Funakoshi, Junko Soejima,

American Journal of Respiratory and Critical Care Medicine · 2006 · 142 citations · 34 references

DOI

Abstract

These observations suggest that HMGB1 could be one of the deteriorating factors in the development of VILI.

References

34

Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome

New England Journal of Medicine · 2000 · 12.7K citations · Full text

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Paola Scaffidi, Tom Misteli, Marco E. Bianchi · Nature · 2002 · 4.1K citations

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HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations

High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes

Haichao Wang, Karin Palmblad, Ann-Charlotte Aveberger et al. · The Journal of Experimental Medicine · 2000 · 1.4K citations · Full text

Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model.

Louis A. Tremblay, Franco Valenza, Sérgio Pinto Ribeiro et al. · Journal of Clinical Investigation · 1997 · 1.3K citations · Full text

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