Intratumor administration of fusogenic liposomes containing fragment A of diphtheria toxin suppresses tumor growth

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Glen Dranoff, Elizabeth M. Jaffee, A Lazenby et al. · Proceedings of the National Academy of Sciences · 1993 · 2.8K citations

Medicine, Immunology, Oncology +17

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

F Szoka, Demetrios Papahadjopoulos · Proceedings of the National Academy of Sciences · 1978 · 2.3K citations · Full text

Natural Sciences, Biochemistry, Biophysics +16

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

Gary J. Nabel, E G Nabel, Zhiyong Yang et al. · Proceedings of the National Academy of Sciences · 1993 · 890 citations

Medicine, Biotechnology, Oncology +17

One molecule of diphtheria toxin fragment a introduced into a cell can kill the cell

Masaru Yamaizumi, Eisuke Mekada, Tsuyoshi Uchida et al. · Cell · 1978 · 754 citations

Life Sciences, Cell Biology, Immunology +7

Treatment of Established Renal Cancer by Tumor Cells Engineered to Secrete Interleukin-4

Paul T. Golumbek, Audrey J. Lazenby, Hyam I. Levitsky et al. · Science · 1991 · 731 citations

Medicine, Immunology, Oncology +17