Concepedia

Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosis

Patrizia D’Amelio, Anastasia Grimaldi, Stefania Di Bella, Stefano Brianza, Maria Angela Cristofaro, Cristina Tamone, Giuliana Giribaldi, Daniela Ulliers, Gianpiero Pescarmona, Giancarlo Isaia

Bone · 2008 · 331 citations · 36 references

DOIFull text

Open access

Concepts

References

36

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Young‐Yun Kong, Hiroki Yoshida, Ildiko Sarosi et al. · Nature · 1999 · 3.4K citations

, , +14

TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

Jonathan Lam, Sunao Takeshita, Jane E. Barker et al. · Journal of Clinical Investigation · 2000 · 1.4K citations · Full text

, , +17

Human housekeeping genes are compact

Eli Eisenberg, Erez Y. Levanon · Trends in Genetics · 2003 · 726 citations

, , +8

Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-α

Simone Cenci, M. Neale Weitzmann, Cristiana Roggia et al. · Journal of Clinical Investigation · 2000 · 696 citations · Full text

, , +17

Role of RANK ligand in mediating increased bone resorption in early postmenopausal women

Guitty Eghbali-Fatourechi, Sundeep Khosla, Arunik Sanyal et al. · Journal of Clinical Investigation · 2003 · 694 citations

, , +17