Laboratory Animals · 2006 · 67 citations · 1 references
Veterinary MedicineAnimal SciencesGeneticsAnimal WelfareGenetic EngineeringTransgenic Animal ModelsAnimal Welfare AssessmentRodent EthicsRodent GeneticsRodent WelfareWelfare AssessmentWelfare IndicatorsBest Practice StandardBiomedical Research EthicsEthics Of Biomedical ExperimentationLaboratory Animal WelfareMouse WelfareTransgenic Animal EthicsTransgenic MiceTransgenic Mouse Models
In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.
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Refinement and reduction in production of genetically modified mice
Vicky Robinson, David B. Morton, Diana Anderson et al. · Laboratory Animals · 2003 · 64 citations · Full text