British Journal of Urology · 2010 · 128 citations · 22 references
MedicineSurgeryUrologyOncologic SurgeryProstate DiseaseUrologic SurgeryErectile DysfunctionMinimally Invasive Urologic SurgeryProstate SurgeryRadical ProstatectomyRobot-assisted SurgeryUrinary Continence AssessmentBilateral Nerve-sparing ProstatectomyPhosphodiesterase Type 5 Inhibitor TherapyPhosphodiesterase Type 5 InhibitorsPost-prostatectomy Continence AssessmentPostoperative Erectile DysfunctionRobot-assisted Radical ProstatectomyRobotic ProstatectomyRobotic-assisted Radical Prostatectomy
OBJECTIVE: • To evaluate early trifecta outcomes after robotic-assisted radical prostatectomy (RARP) performed by a high-volume surgeon. PATIENTS AND METHODS: • We evaluated prospectively 1100 consecutive patients who underwent RARP performed by one surgeon. In all, 541 men were considered potent before RARP; of these 404 underwent bilateral full nerve sparing and were included in this analysis. • Baseline and postoperative urinary and sexual functions were assessed using self-administered validated questionnaires. • Postoperative continence was defined as the use of no pads; potency was defined as the ability to achieve and maintain satisfactory erections for sexual intercourse >50% of times, with or without the use of oral phosphodiesterase type 5 inhibitors; Biochemical recurrence (BCR) was defined as two consecutive PSA levels of >0.2 ng/mL after RARP. • Results were compared between three age groups: Group 1, ≤ 55 years, Group 2, 56-65 years and Group 3, >65 years. RESULTS: • The trifecta rates at 6 weeks, 3, 6, 12, and 18 months after RARP were 42.8%, 65.3%, 80.3%, 86% and 91%, respectively. • There were no statistically significant differences in the continence and BCR-free rates between the three age groups at all postoperative intervals analysed. • Nevertheless, younger men had higher potency rates and shorter time to recovery of sexual function when compared with older men at 6 weeks, 3, 6 and 12 months after RARP (P < 0.01 at all time points). • Similarly, younger men had higher trifecta rates at 6 weeks, 3 and 6 months after RARP compared with older men (P < 0.01 at all time points). CONCLUSION: • RARP offers excellent short-term trifecta outcomes when performed by an experienced surgeon. • Younger men had higher overall trifecta rates when compared with older men at 6 weeks, 3 and 6 months after RARP.
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AJCC Cancer Staging Manual. 6th ed
FL Greene, DL Page, Fleming Id et al. · 2002 · 2.3K citations
Radical Prostatectomy versus Watchful Waiting in Early Prostate Cancer
Anna Bill‐Axelson, Lars Holmberg, Mirja Ruutu et al. · New England Journal of Medicine · 2011 · 1.9K citations
Radical Prostatectomy versus Watchful Waiting in Early Prostate Cancer
Anna Bill‐Axelson, Lars Holmberg, Mirja Ruutu et al. · New England Journal of Medicine · 2005 · 1.1K citations · Full text