Concepedia

The Clock Genes Period 2 and Cryptochrome 2 Differentially Balance Bone Formation

Erik Maronde, Arndt F. Schilling, Sebastian Seitz, Thorsten Schinke, Isabelle Schmutz, Gijsbertus T. J. van der Horst, Michael Amling, Urs Albrecht

PLoS ONE · 2010 · 113 citations · 30 references

DOIFull text

Open access

Abstract

This indicates that Cry2 and Per2 affect distinct pathways in the regulation of bone volume with Cry2 influencing mostly the osteoclastic cellular component of bone and Per2 acting on osteoblast parameters.

References

30

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

A. M. Parfitt, Marc K. Drezner, Francis H. Glorieux et al. · Journal of Bone and Mineral Research · 1987 · 5K citations

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Bone Histomorphometry : Standardization of Nomenclature, Symbols, and Units

A. M. Parfitt, M. K. Drezner, Francis H. Glorieux et al. · Journal of Bone and Mineral Research · 1987 · 3.3K citations

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PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Seung Hee Yoo, Shin Yamazaki, Phillip L. Lowrey et al. · Proceedings of the National Academy of Sciences · 2004 · 2.3K citations · Full text

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms

Gijsbertus T. J. van der Horst, Manja Muijtjens, Kumiko Kobayashi et al. · Nature · 1999 · 1.4K citations

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Interacting Molecular Loops in the Mammalian Circadian Clock

Lauren P. Shearman, Sriram Sathyanarayanan, David R. Weaver et al. · Science · 2000 · 1.3K citations

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