Publication | Open Access
Isolation of an Integron-Borne <i>bla</i> <sub>VIM-4</sub> Type Metallo-β-Lactamase Gene from a Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> Clinical Isolate in Hungary
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2004
Year
GeneticsAntibiotic ResistanceBacterial PathogensNovel BlaDrug ResistanceHigh Structural SimilarityClass 1Infection ControlAntimicrobial ResistanceHealth SciencesPathogen CharacterizationMolecular MicrobiologyClinical MicrobiologyAntimicrobial Resistance GeneAntimicrobial SusceptibilityAntibioticsPathogenesisMicrobiologyMedicine
The first integron-borne metallo-beta-lactamase gene was isolated in Hungary. The bla(VIM-4) gene is located on a class 1 integron that also carries a novel bla(OXA)-like gene. The integron is harbored by a serotype O12 Pseudomonas aeruginosa strain and shows high structural similarity to integrons isolated in Greece and Poland.
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