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Isolation of an Integron-Borne <i>bla</i> <sub>VIM-4</sub> Type Metallo-β-Lactamase Gene from a Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> Clinical Isolate in Hungary

Balázs Libisch, M Gacs, K Csiszár, M. Muzslay, László Rókusz, M. Füzi

Antimicrobial Agents and Chemotherapy · 2004 · 54 citations · 17 references

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Concepts

Abstract

The first integron-borne metallo-beta-lactamase gene was isolated in Hungary. The bla(VIM-4) gene is located on a class 1 integron that also carries a novel bla(OXA)-like gene. The integron is harbored by a serotype O12 Pseudomonas aeruginosa strain and shows high structural similarity to integrons isolated in Greece and Poland.

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