Concepedia

PAK1 Mediates Resistance to PI3K Inhibition in Lymphomas

Katherine Walsh, Matthew McKinney, Cassandra Love, Qingquan Liu, Alice C. Fan, Amee B. Patel, Jason P. Smith, Anne Beaven, Dereje D. Jima, Sandeep S. Davé

Clinical Cancer Research · 2013 · 50 citations · 24 references

DOIFull text

Open access

Abstract

Thus, we show that PI3K inhibition is broadly effective in lymphomas and PAK1 is a key modulator of resistance to PI3K inhibition.

References

24

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

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