Concepedia

Comparison of antitumor effects of daunorubicin covalently linked to poly-l-amino acid carriers

Franco Zunino, Giuseppina Savi, Fernando C. Giuliani, Romolo A. Gambetta, Rosanna Supino, Stella Tinelli, Gabriella Pezzoni

European Journal of Cancer and Clinical Oncology · 1984 · 34 citations · 17 references

DOI

Concepts

References

17

Reduction of Doxorubicin Cardiotoxicity by Prolonged Continuous Intravenous Infusion

Sewa S. Legha, Robert S. Benjamin, Bruce R. MacKay et al. · Annals of Internal Medicine · 1982 · 769 citations

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The Anticancer Agent Adriamycin Can Be Actively Cytotoxic Without Entering Cells

Thomas R. Triton, Gene K. Yee · Science · 1982 · 572 citations

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Cis-aconityl spacer between daunomycin and macromolecular carriers: A model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate

Wei‐Chiang Shen, Hugues J.‐P. Ryser · Biochemical and Biophysical Research Communications · 1981 · 271 citations

, , +17

A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies.

A. Trouet, Michèle Masquelier, R. Baurain et al. · Proceedings of the National Academy of Sciences · 1982 · 233 citations

, , +16

Suppression of tumour growth in mice by a drug–antibody conjugate using a novel approach to linkage

G. F. Rowland, G. J. O’Neill, D. A. L. Davies · Nature · 1975 · 164 citations

, , +13