Neurology · 2000 · 172 citations · 9 references
Life SciencesNeurologyNeuroscienceClinical NeuroscienceMotor NeuroscienceNeuroplasticityDemyelinating DisordersDiffuse Axonal InjuryFunctional NeuroimagingFunctional NeurologyMotor RecoveryMultiple SclerosisFunctional MriIschemic Axonal InjuryMotor Cortex OrganizationMotor Cortex PhysiologyMotor Cortex ReorganizationStructural MriStructural ReorganizationTraumatic Axonal Injury
A patient was followed after the new onset of hemiparesis from relapse of MS with serial MR spectroscopy and functional MRI. The association of clinical improvement with recovery of N-acetylaspartate, a marker of neuronal integrity, and progressive reduction of abnormally large functional MRI cortical activation with movement demonstrates that dynamic reorganization of the motor cortex accompanies remission of MS.
9
Possible involvement of primary motor cortex in mentally simulated movement
Muriel Roth, Jean Decety, Monica Raybaudi et al. · Neuroreport · 1996 · 494 citations