Concepedia

A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis

Jin-Feng Zhou, Rani S. Sellers, Jiu-feng Li, Andrew Nguyen, Yubao Wang, Amos Orlofsky, Qiang Liu, David Hume, Jeffrey W. Pollard, Leonard H. Augenlicht,

American Journal Of Pathology · 2009 · 221 citations · 47 references

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47

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

Isao Okayasu, Shigeru Hatakeyama, Masahiro Yamada et al. · Gastroenterology · 1990 · 2.4K citations

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IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei I. Grivennikov, Eliad Karin, Janoš Terzić et al. · Cancer Cell · 2009 · 2.1K citations · Full text

, , +16

Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation

Zilong Wen, Zhong Zhong, James Darnell · Cell · 1995 · 2K citations · Full text

, , +10

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

Gerald P. Morris, Paul L. Beck, Margaret S. Herridge et al. · Gastroenterology · 1989 · 1.7K citations

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Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Johan H. van Es, Mariëlle van Gijn, Orbicia Riccio et al. · Nature · 2005 · 1.5K citations · Full text

, , +15