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Inhibition of human placental endothelial cell proliferation and angiogenesis by netrin-4

Mbarka Dakouane‐Giudicelli, Sophie Brouillet, Waël Traboulsi, Antoine Torre, Guillaume Vallat, Sammy Si Nacer, Marion Vallée, Jean‐Jacques Feige, Nadia Alfaidy, Philippe de Mazancourt

Placenta · 2015 · 22 citations · 21 references

DOIFull text

Open access

Abstract

This is the first report of an anti-angiogenic activity of netrin-4 in human placenta. This study brings new insights into netrin-4 roles in placental angiogenesis and suggests possible involvements of netrin-4 in angiogenesis-related pathologies such as IUGR.

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