Admission Troponin T Level Predicts Clinical Outcomes, TIMI Flow, and Myocardial Tissue Perfusion After Primary Percutaneous Intervention for Acute ST-Segment Elevation Myocardial Infarction

Evangelos Giannitsis, Margit Müller-Bardorff, Stephanie Lehrke, Uwe Wiegand, Ralph Tölg, Britta Weidtmann, Franz Hartmann, Gert Richardt, Hugo A. Katus

Circulation · 2001 · 107 citations · 31 references

Abstract

cTnT predicts poorer clinical outcomes, lower rates of postprocedural TIMI 3 flow, and more severely compromised myocardial perfusion despite normal epicardial flow. Thus, a cTnT-positive patient may require more aggressive adjunctive therapy when treated by percutaneous coronary intervention. The impact of preexisting or evolving microvascular dysfunction and the effect of therapies that target myocardial perfusion require further prospective evaluation.

References

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