Concepedia
Clinical Cancer Research · 2008 · 147 citations · 32 references
Open access
This study shows epigenetic progression in the earliest stages of glandular neoplasia of the lung and has implications for early lung cancer detection.
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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.6K citations · Full text
Epigenetic Change, Genetics, Dna Methylation +21
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
Manel Esteller, Stanley R. Hamilton, P C Burger et al. · PubMed · 1999 · 1.3K citations
Common Event, Epigenetic Change, Genetics +16
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
Hiromu Suzuki, D. Neil Watkins, Kam-Wing Jair et al. · Nature Genetics · 2004 · 1.1K citations · Full text
Sfrp Genes, Radiation Oncology, Medicine +9
Aberrant methylation of <i>p16</i> <sup>INK4a</sup> is an early event in lung cancer and a potential biomarker for early diagnosis
Steven A. Belinsky, Kristen J. Nikula, William A. Palmisano et al. · Proceedings of the National Academy of Sciences · 1998 · 959 citations · Full text
Cancer Facts & Figures 2004
Paul Betts, Brenda Mokry, David R. Risser et al. · 2004 · 844 citations
Cancer Risk, Cancer Epidemiology, Medicine +7