Concepedia

Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs.

Alvin Berger, Dietrich Rein, E Kratky, Irina Monnard, Hassan Hajjaj, Isabelle Meirim, Christelle Piguet-Welsch, Jonas Hauser, Katherine Macé, Peter Niederberger

Lipids in Health and Disease · 2004 · 90 citations · 61 references

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Abstract

Overall, Gl has potential to reduce LDL cholesterol in vivo through various mechanisms. Next steps are to: fully characterize bioactive components in lipid soluble/insoluble fractions; evaluate bioactivity of isolated fractions; and examine human cholesterol lowering properties. Innovative new cholesterol-lowering foods and medicines containing Gl are envisioned.

References

61

Therapeutic Effects of Substances Occurring in Higher Basidiomycetes Mushrooms: A Modern Perspective

Alexander L. Weis, Solomon P. Wasser · Critical Reviews in Immunology · 1999 · 769 citations

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Micro assay for 3-hdyroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts

David J. Shapiro, Jeffrey L. Nordstrom, Jonathan J. Mitschelen et al. · Biochimica et Biophysica Acta (BBA) - Enzymology · 1974 · 407 citations

, , +14

BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis

Peter A. Edwards, Heidi R. Kast-Woelbern, Andrew M. Anisfeld · Journal of Lipid Research · 2002 · 384 citations · Full text

Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits.

Phạm T.T., Gregorio Gil, T C Südhof et al. · Proceedings of the National Academy of Sciences · 1986 · 335 citations

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Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens.

Andrea M. A. Pfeifer, K E Cole, Duane T. Smoot et al. · Proceedings of the National Academy of Sciences · 1993 · 248 citations · Full text