Premedication for jejunal biopsy in childhood using intravenous diazepam and metoclopramide.

Abstract

Premedicationdfor jejunal biopsy in childhood using intravenous diazepam and metoclopramide Small bowel biopsy is essential for the diagnosis of coeliac disease (Anderson, Gracey, and Burke, 1972), as well as being useful in the investigation and follow-up of a number of other enteropathies. The technique should preferably be used by those who will have continuing experience and who are backed up by expert help in the histological and biochemical analysis of the mucosal specimens. The Watson Paediatric Capsule* has proved its quality and safety over many years (Townley and Barnes, 1973). Good fluoroscopy facilities are also essential. The test obviously remains a worrying procedure to the child, with unpleasant memories, as we often find from referred patients and mothers. We do not share the experience of Townley and An unco-operative patient will sometimes mean failure to obtain a mucosal specimen with refusal of a repeat performance.