Concepedia

Deficits in Transcriptional Regulators of Cortical Parvalbumin Neurons in Schizophrenia

David W. Volk, Takurou Matsubara, Siyu Li, Elizabeth J. Sengupta, Yoshio Minabe, Allan R. Sampson, Takanori Hashimoto, David A. Lewis

American Journal of Psychiatry · 2012 · 158 citations · 43 references

DOIFull text

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Abstract

These data suggest that in a subset of individuals with schizophrenia, Lhx6 deficits may contribute to a failure of some cortical parvalbumin and somatostatin neurons to successfully migrate or develop a detectable GABA-ergic phenotype.

References

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