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Risk factors for nephrotoxicity onset associated with polymyxin B therapy

Yanina Dubrovskaya, Nishant Prasad, Yuman Lee, Diana Esaian, Deborah A. Figueroa, Vincent H. Tam

Journal of Antimicrobial Chemotherapy · 2015 · 63 citations · 14 references

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Abstract

Risk factors for nephrotoxicity onset associated with polymyxin B were identified. In conjunction with susceptibility and other pharmacokinetic/pharmacodynamic data, our results can be used to optimize treatment for MDR Gram-negative infections.

References

14

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Vincent H. Tam, Amy N. Schilling, Giao Vo et al. · Antimicrobial Agents and Chemotherapy · 2005 · 204 citations · Full text

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Higher Incidence of Acute Kidney Injury With Intravenous Colistimethate Sodium Compared With Polymyxin B in Critically Ill Patients at a Tertiary Care Medical Center

Darowan S. Akajagbor, Sharon Wilson, Kapana D. Shere-Wolfe et al. · Clinical Infectious Diseases · 2013 · 203 citations · Full text

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Polymyxin B Nephrotoxicity and Efficacy against Nosocomial Infections Caused by Multiresistant Gram-Negative Bacteria

John P. Ouderkirk, Jill A. Nord, Glenn Turett et al. · Antimicrobial Agents and Chemotherapy · 2003 · 188 citations · Full text

<i>In Vitro</i> Assessment and Multicenter Cohort Study of Comparative Nephrotoxicity Rates Associated with Colistimethate versus Polymyxin B Therapy

Kady Phe, Yuman Lee, Patrick M. McDaneld et al. · Antimicrobial Agents and Chemotherapy · 2014 · 178 citations · Full text

, , +15