Concepedia

Polymyxin Toxicity

Polymyxin Toxicity is a pharmacological adverse effect characterized by nephrotoxicity and neurotoxicity arising from the clinical use of polymyxin antibiotics, particularly colistin and polymyxin B, due to their detergent-like disruption of bacterial and mammalian cell membranes.

191

Publications

9.9K

Citations

889

Authors

309

Institutions

Publications per year

2017–2026

73

Parents

Publications

191

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

Willy Chin, Guansheng Zhong, Qinqin Pu et al. · Nature Communications · 2018 · 331 citations · Full text

, , +17

THE PROPERTIES AND MODE OF ACTION OF THE POLYMYXINS

B. A. Newton · Bacteriological Reviews · 1956 · 290 citations · Full text

, , +6

Clinical and Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing Position Statements on Polymyxin B and Colistin Clinical Breakpoints

Michael J. Satlin, James S. Lewis, Melvin P. Weinstein et al. · Clinical Infectious Diseases · 2020 · 246 citations

, , +16

Toxicity after prolonged (more than four weeks) administration of intravenous colistin

Matthew E. Falagas, Michael Rizos, Ioannis A. Bliziotis et al. · BMC Infectious Diseases · 2005 · 242 citations · Full text

, , +15

Polymyxin B Nephrotoxicity and Efficacy against Nosocomial Infections Caused by Multiresistant Gram-Negative Bacteria

John P. Ouderkirk, Jill A. Nord, Glenn Turett et al. · Antimicrobial Agents and Chemotherapy · 2003 · 189 citations · Full text

, , +13

1–5 of 191

Authors

889

  1. JL
    Jian Li

    Monash University, Australia

    17 publications · 1.1K citations

    16

    h-index

  2. TV
    Tony Velkov

    Monash University, Australia

    16 publications · 970 citations

    15

    h-index

  3. MA
    Mohammad Abul Kalam Azad

    Monash University, Australia

    10 publications · 717 citations

    10

    h-index

  4. RL
    Roger L. Nation

    Monash University, Australia

    9 publications · 721 citations

    9

    h-index

  5. KD
    Kade D. Roberts

    Monash University, Australia

    8 publications · 630 citations

    8

    h-index

1–5 of 889

Institutions

309

  1. Monash University

    Melbourne, Australia

    16 h-index

    131 publications

    9.2K citations

  2. Australian Regenerative Medicine Institute

    Clayton, Australia

    9 h-index

    35 publications

    2.6K citations

  3. The University of Melbourne

    Melbourne, Australia

    7 h-index

    9 publications

    333 citations

  4. University of Helsinki

    Helsinki, Finland

    5 h-index

    9 publications

    475 citations

  5. Purdue University West Lafayette

    West Lafayette, United States

    4 h-index

    11 publications

    636 citations

  6. Universidade de São Paulo

    São Paulo, Brazil

    4 h-index

    12 publications

    1K citations

  7. Helsinki University Hospital

    Helsinki, Finland

    4 h-index

    4 publications

    290 citations

  8. China Agricultural University

    Beijing, China

    3 h-index

    18 publications

    480 citations

1–8 of 309

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 27 publications · 1.9K citations

    24

    h-index

  2. PubMed

    Repository · 12 publications · 272 citations

    11

    h-index

  3. ACS Infectious Diseases

    8 publications · 432 citations

    8

    h-index

  4. Journal of Antimicrobial Chemotherapy

    JAC · 5 publications · 296 citations

    5

    h-index

  5. Journal of Medicinal Chemistry

    4 publications · 217 citations

    4

    h-index

1–5