Concepedia

Elucidation of Essential and Nonessential Genes in the <i>Haemophilus influenzae</i> Rd Cell Wall Biosynthetic Pathway by Targeted Gene Disruption

Catherine M. Trepod, John E. Mott

Antimicrobial Agents and Chemotherapy · 2005 · 14 citations · 4 references

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Abstract

Targeted gene disruption by in vitro transposon mutagenesis has been used to identify the genes required for biosynthesis of the Haemophilus influenzae Rd cell wall under standard cultivation conditions. Of the 28 genes known to be associated with the cell wall biosynthetic pathway, 14 were determined to be essential.

References

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Systematic identification of essential genes by <i>in vitro mariner</i> mutagenesis

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Genome Scanning in Haemophilus influenzae for Identification of Essential Genes

Karl Reich, Linda E. Chovan, Paul Hessler · Journal of Bacteriology · 1999 · 42 citations · Full text

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Identification of the <i>Haemophilus influenzae tolC</i> Gene by Susceptibility Profiles of Insertionally Inactivated Efflux Pump Mutants

Catherine M. Trepod, John E. Mott · Antimicrobial Agents and Chemotherapy · 2004 · 31 citations · Full text

, , +9