Concepedia

Nanoparticles Encapsulating Hepatitis B Virus Cytosine-Phosphate-Guanosine Induce Therapeutic Immunity against HBV Infection

Shujuan Lv, Jun Wang, Shuang Dou, Xianzhu Yang, Xiang Ni, Rui Sun, Zhigang Tian, Haiming Wei

Hepatology · 2013 · 47 citations · 18 references

DOIFull text

Open access

Abstract

Endogenous HBV-CpG ODNs from the HBV genome induce IFN-α production so that nanoparticle-encapsulated HBV-CpG may act as an HBsAg vaccine adjuvant and may also represent a potent therapeutic agent for the treatment of chronic HBV infection.

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