Clinical Infectious Diseases · 2010 · 204 citations · 15 references
Life SciencesInfectious DiseasesMicrobiologyAntimicrobial ResistanceMedical MicrobiologyMicrobial GeneticsAntibiotic ResistanceAntibiotic Resistance GeneticsBacterial InfectionsResistance EpidemiologyRespiratory InfectionsRespiratory Tract InfectionsAntibiotic Resistance In Respiratory PathogensDrug Resistance TestingMacrolide Resistance GenesMacrolide Resistance MechanismsMacrolide TherapyMycoplasma InfectionsMycoplasmal Respiratory DiseasePoint Mutations
The resistance rate of 67 Mycoplasma pneumoniae isolates from 356 ambulatory adult patients with respiratory tract infection was 69% (46 of 67). All 46 macrolide-resistant strains harbored point mutations in the 23S ribosomal RNA gene. Patients infected with macrolide-resistant M. pneumoniae required significantly longer durations of antibiotic therapy and had longer time to resolution of fever.
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Complete Sequence Analysis of the Genome of the Bacterium Mycoplasma Pneumoniae
Ralf Himmelreich, H. Hilbert, H. Plagens et al. · Nucleic Acids Research · 1996 · 1.2K citations · Full text
Mayumi Matsuoka, Mitsuo Narita, Norio Okazaki et al. · Antimicrobial Agents and Chemotherapy · 2004 · 253 citations · Full text
Norio Okazaki, Mitsuo Narita, Satoshi Yamada et al. · Microbiology and Immunology · 2001 · 189 citations · Full text