Role of Right Ventricle and Dynamic Pulmonary Hypertension on Determining ΔVO ₂ /ΔWork Rate Flattening

Abstract

In patients symptomatic for dyspnea, the occurrence of ΔVO2/ΔWR flattening reflects a significantly impaired functional phenotype whose main cardiac determinants are the excessive systolic pulmonary artery pressure increase and the reduced peak right ventricular longitudinal systolic function.