First Nosocomial Outbreak of <i>Pseudomonas aeruginosa</i> Producing an Integron-Borne Metallo-β-Lactamase (VIM-2) in the United States

Abstract

Carbapenemases are rare in the United States. This is the first report of a United States nosocomial outbreak of pan-resistant Pseudomonas aeruginosa infections due to an integron-borne metallo-beta-lactamase, VIM-2. This emergence of carbapenemases on mobile genetic elements in the United States warrants surveillance.