Concepedia

Publication | Open Access

GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer

DOIFull Paper Access

193

Citations

37

References

2009

Year

Debby M.E.I. Hellebrekers, Marjolein H.F.M. Lentjes, Sandra M. van den Bosch, Veerle Melotte, Kathleen L.J. Daenen, Kim M. Smits, Yoshimitsu Akiyama, Yasuhito Yuasa, Silvia Sanduleanu, Carolina A.J. Khalid-de Bakker,
Clinical Cancer Research

Abstract

Methylation of GATA4/5 is a common and specific event in colorectal carcinomas, and GATA4/5 exhibit tumor suppressive effects in colorectal cancer cells in vitro. GATA4 methylation in fecal DNA may be of interest for colorectal cancer detection.

References

YearCitations

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