Prediction of Fetal Infection in Cases With Cytomegalovirus Immunoglobulin M in the First Trimester of Pregnancy: A Retrospective Cohort

Abstract

This study demonstrates a significant association between the risk of vertical transmission and the avidity index combined with CMV PCR in maternal serum or IgG titers. This allows calculation of incremental risk of fetal transmission upon which informed choice can be based and could lead to a better pickup rate of fetal infection while decreasing unnecessary invasive procedures.