Common Variants in <i>HSPB7</i> and <i>FRMD4B</i> Associated With Advanced Heart Failure

Abstract

Our findings identify regions containing HSPB7 and FRMD4B as novel susceptibility loci for advanced heart failure. More broadly, in an era of genome-wide association studies, we demonstrate how knowledge of candidate genes can be leveraged as a complementary strategy to discern the genetics of complex disorders.