Chemistry - A European Journal · 2014 · 21 citations · 23 references
Natural SciencesBiochemistryBiophysicsBiological Transport PhenomenaMembrane BiochemistryMembrane BiophysicsBiological MembranesIon ChannelsIon PermeationMembrane TransportTransport Across Biological MembranesTransport In CellsIon Transport MembranesIon Transport Through Membrane ChannelsTransmembrane Transport KineticsTransport Mechanisms
We describe the molecular parameters governing the transmembrane activity of imidazolium-functionalized anion transporters and present a detailed mechanistic study. These ionophores adopt a mobile-carrier mechanism for short methyl and butyl chains, a combined mobile-carrier/transmembrane-pore mechanism for octyl and dodecyl chains, and form transmembrane aggregates for hexadecyl chains.
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HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain
Edward C. Emery, Gareth T. Young, Esther Berrocoso et al. · Science · 2011 · 352 citations