Synthesis, Anion‐Binding Properties, and In Vitro Anticancer Activity of Prodigiosin Analogues

Abstract

Pro and anti: Recognition of chloride ion and through-membrane H+/Cl− ion transport (“symport”) could account for the biological effects (anticancer activity) of prodigiosin, as inferred from model studies involving pyrrole-based anion receptors designed to mimic the key features of this naturally occurring pigment (see picture). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z501740_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.