A Detection System Based on Giant Magnetoresistive Sensors and High‐Moment Magnetic Nanoparticles Demonstrates Zeptomole Sensitivity: Potential for Personalized Medicine

Balasubramanian Srinivasan, Yuanpeng Li, Ying Jing, Yun-Hao Xu, Xiaofeng Yao, Chengguo Xing, Jian‐Ping Wang

Angewandte Chemie International Edition · 2009 · 139 citations · 24 references

Concepts

Abstract

Zeptomole detector: A highly sensitive giant-magnetoresistive chip and FeCo nanoparticles can be used to linearly detect 600-4500 copies of streptavidin. Under unoptimized conditions, this system also detects human IL-6 with a sensitivity 13-times higher than that of standard ELISA techniques.

References

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