Gold(<scp>I</scp>)‐Catalyzed 5‐<i>endo</i>‐<i>dig</i> Carbocyclization of Acetylenic Dicarbonyl Compounds

Abstract

Cyclopentenoid structures including compounds containing vinyl iodide, 1,3-diene, and heterocyclic moieties are obtained through the gold(I)-catalyzed 5-endo-dig addition of β-dicarbonyl compounds to unactivated alkynes under neutral conditions and at room temperature (RT). Both monocyclic and bicyclic cyclopentenes can be formed in excellent yields and with good diastereoselectivity (see scheme).