Optics Letters · 1994 · 83 citations · 7 references
EngineeringBiomedical EngineeringBiophysicsBiomedical OpticsBiophotonicsSpectroscopyAbsorption In TissueLight-tissue InteractionOptical SpectroscopyPhoton TransportScattering In TissueTissue Optical PropertiesAvalanche DetectionAvalanche Photodiode DetectorsLaser Diode ModulationOptical Absorption In TissueOptical PropertiesPhoton MigrationPhoton Migration ModelingPhoton Transport In Tissue
We describe a novel frequency-domain photon migration instrument employing direct diode laser modulation and avalanche photodiode detection, which is capable of noninvasively determinating the optical properties of biological tissues in near real time. An infinite medium diffusion model was used to extract absorption and transport scattering coefficients from 300-kHz to 800-MHz photon-density wave phase data. Optical properties measured in tissue-simulating solutions at 670 nm agreed to within 10% of those expected.
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Light scattering in lntralipid-10% in the wavelength range of 400–1100 nm
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Properties of photon density waves in multiple-scattering media
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Refraction of diffuse photon density waves
M. A. O’Leary, D. A. Boas, B. Chance et al. · Physical Review Letters · 1992 · 186 citations