Concepedia

Regulatory Insertion Removal Restores Maturation, Stability and Function of ΔF508 CFTR

Andrei A. Aleksandrov, Pradeep Kota, Luba A. Aleksandrov, Lihua He, Tim Jensen, Liying Cui, Martina Gentzsch, Nikolay V. Dokholyan, John R. Riordan

Journal of Molecular Biology · 2010 · 114 citations · 52 references

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52

Degradation of CFTR by the ubiquitin-proteasome pathway

Cristina L. Ward, Satoshi ŌMURA, Ron R. Kopito · Cell · 1995 · 1.3K citations · Full text

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Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

Gerene M. Denning, Matthew P. Anderson, Jane F. Amara et al. · Nature · 1992 · 1.2K citations

, , +9

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

Timothy J. Jensen, Melinda A. Loo, S. Pind et al. · Cell · 1995 · 898 citations · Full text

, , +12

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

Wilfried Dalemans, Pascal Barbry, Guy Champigny et al. · Nature · 1991 · 700 citations

, , +13

Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis

Xiaodong Wang, John D. Venable, Paul LaPointe et al. · Cell · 2006 · 599 citations · Full text

, , +12