Concepedia

Publication | Open Access

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase a oncogene

DOIFull Paper Access

41

Citations

28

References

2012

Year

Maria Meehan, Laavanya Parthasarathi, Niamh Moran, Caroline A. Jefferies, Niamh H. Foley, Elisa Lazzari, Derek Murphy, Jacqueline Ryan, Berenice Ortiz, Armida W. M. Fabius,
Molecular Cancer

Abstract

PTPRD has a tumor suppressor function in neuroblastoma through AURKA dephosphorylation and destabilization and a downstream destabilization of MYCN protein, representing a novel mechanism for the function of PTPRD in neuroblastoma.

References

YearCitations

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