Platelets Direct Monocyte Differentiation Into Epithelioid-Like Multinucleated Giant Foam Cells With Suppressive Capacity Upon Mycobacterial Stimulation - Concepedia

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Platelets Direct Monocyte Differentiation Into Epithelioid-Like Multinucleated Giant Foam Cells With Suppressive Capacity Upon Mycobacterial Stimulation

DOI Full Paper Access

53

Citations

36

References

2014

Year

Yonghong Feng, Anca Dorhoi, Hans‐Joachim Mollenkopf, Hongyun Yin, Zhengwei Dong, Ling Mao, Jun Zhou, Aixiao Bi, Stephan Weber, Jeroen Maertzdorf,

The Journal of Infectious Diseases

Abstract

Platelets drive macrophage differentiation into MNGCs with characteristics of epithelioid, foam, and giant cells observed in tuberculosis granulomas. Our data define platelets as novel participants in tuberculosis pathogenesis.

References

	Year	Citations

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