Concepedia

бNAT2*6A��, a haplotype of the бN��-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis

Norihide Higuchi

World Journal of Gastroenterology · 2007 · 63 citations · 26 references

DOIFull text

Open access

Abstract

The present study shows that NAT2 is one of the determinants of anti-TB drug-induced hepatotoxicity. Moreover, the haplotypes, NAT2 4 and NAT2 6A, are useful new biomarkers for predicting anti-TB drug-induced hepatotoxicity.

References

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