Concepedia

End-stapled homo and hetero collagen triple helices: a click chemistry approach

Cillian Byrne, Paul McEwan, Jonas Emsley, Peter M. Fischer, Weng C. Chan

Chemical Communications · 2010 · 30 citations · 17 references

DOIFull text

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Concepts

Abstract

A CuAAC reaction was established for modular synthesis of end-stapled homo- and hetero-triple helical peptides, generating "clicked" macro-assemblies with enhanced thermal stability.

References

17

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.5K citations

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Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

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Crystal Structure of the Extracellular Segment of Integrin αVβ3

Jian-Ping Xiong, Thilo Stehle, Beate Diefenbach et al. · Science · 2001 · 1.3K citations · Full text

, , +17

Structural Basis of Collagen Recognition by Integrin α2β1

Jonas Emsley, Christopher G. Knight, Richard W. Farndale et al. · Cell · 2000 · 994 citations · Full text

, , +16

Use of Synthetic Peptides to Locate Novel Integrin α2β1-binding Motifs in Human Collagen III

Nicolas Raynal, Samir W. Hamaia, Pia Siljander et al. · Journal of Biological Chemistry · 2005 · 188 citations · Full text

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