Canadian Journal of Physiology and Pharmacology · 1966 · 339 citations · 2 references
EngineeringBioengineeringBiotechnologyBiomaterialsDrug DeliveryPolymer ChemistryBiological MembranesCell EncapsulationMembrane FabricationMembrane MaterialsPolymer MembranesPolymeric MembranesAqueous-phase ChemistryCell-encapsulating MaterialsInterfacial PolymerizationMicroparticlesPolymeric MicrocapsulesPolymeric MicroparticlesSemipermeable MembranesThin-film Membranes
Methods have been developed for depositing thin stable semipermeable polymer membranes around aqueous microdroplets (mean diameter down to 5 μ or less) by either interfacial polymerization or interfacial coacervation. The enclosed aqueous phase may contain enzymes or other proteins, cell fragments, or intact cells. Examples of methods for preparing such microcapsules are given in detail, and some of their properties are described.
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Lyman C. Craig · Science · 1964 · 77 citations