Angewandte Chemie International Edition · 2011 · 178 citations · 21 references
PharmacyChemical EngineeringMaterials ScienceNanomaterialsPolymer ChemistrySeparation ScienceChromatographic PurificationChromatographyLiquid ChromatographyNanoparticle CharacterizationNanoparticle DispersionsPolymeric NanoparticlesAnalytical Size-exclusion ChromatographyBiomedical ApplicationsChromatographic Separation MechanismsPoly(lactic-co-glycolic Acid) NanoparticlesSize-exclusion Liquid Chromatography
Making even tiny diamonds valuable: Nanodiamonds (NDs) were covalently functionalized with hyperbranched polyglycerol (PG) by ring-opening polymerization to improve their suitability for biomedical applications (see scheme). The PG-grafted NDs were highly soluble not only in pure water (>20 mg mL−1), but also in a buffer (>16 mg mL−1), and were separated according to size by size-exclusion chromatography.
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