Publication | Closed Access
Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation
601
Citations
75
References
1997
Year
EngineeringBiomedical EngineeringTransient ImagingDiffuse Correlation ProbeTissue ImagingOptical PropertiesCorrelation WaveCorrelation Diffusion EquationOptical SystemsBiophysicsRadiologyHealth SciencesTemporal Light CorrelationDynamical PropertiesPhysicsMedical ImagingBiophotonicsMedical Image ComputingOptical ImagingTurbid MediaBiomedical ImagingOptical Coherence Tomography
The diffusion of correlation is used to detect, localize, and characterize dynamical and optical spatial inhomogeneities in turbid media and is accurately modeled by a correlation diffusion equation. We demonstrate experimentally and with Monte Carlo simulations that the transport of correlation can be viewed as a correlation wave {analogous to a diffuse photon-density wave [Phys. Today48, 34 (1995)]} that propagates spherically outward from sources and scatters from macroscopic spatial variations in dynamical and/or optical properties. We demonstrate the utility of inverse scattering algorithms for reconstructing images of the spatially varying dynamical properties of turbid media. The biomedical applicability of this diffuse correlation probe is illustrated in studies of the depth of burned tissues.
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